Last year the Mets had arguably the toughest Interleague schedule in the NL East. So lets compare the Interleague games for this upcoming season.
Mets:
6 vs Yanks
3 vs Rangers
3 vs Angels
3 vs Mariners
Phillies:
3 vs Blue Jays
3 vs Red Sox
3 vs Angels
3 vs Athletics
3 vs Rangers
Braves:
3 vs Athletics
3 vs Angels
3 vs Rangers
3 vs Mariners
3 vs Blue Jays
All three teams (I didn't include the Nationals and the Marlins in this edition, maybe I will in a later one if you all want me to) play the Rangers and the Angels, which for the NL East is a good thing. I feel that the Angels will be in first during Interleague play. Regarding the Rangers, if they are like they were last year, they will have a highly potent offense and no team in the East right now has exceptional pitching.
At least the Phillies face a tough AL East team. Last year the Mets had the Yanks and the Braves had the Sox, so thank God the Phils got the Sox this year, even if it is only for 3 games. Now it is slightly unfair that both the Braves and the Phils got Toronto (and Oakland), (which is due to the 6 games the Mets play against the Yanks).
This year, at least when looking at the teams on paper in preseason terms, interleague looks to be much more even this year.